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November 20, 2025
New AAP Interim Guidance on Leucovorin Use in Autism

The American Academy of Pediatrics (AAP) has released interim guidance on leucovorin (folinic acid) use for children with autism. The AAP does not recommend routine use of leucovorin due to limited evidence on its safety and effectiveness, but supports further research into promising therapies. Resources for clinicians and family discussions are available at the link below.